Non-Invasive Prenatal Test (NIPT)

Safe and accurate NIPT screening from 10 weeks of pregnancy. Screen for Down Syndrome, Edwards Syndrome and Patau Syndrome.

From £279 with results in 5-7 working days

The Non-Invasive Prenatal Test (NIPT) is a safe and highly accurate prenatal screening test that analyses cell-free foetal DNA in the mother’s blood to assess the risk of the most common chromosomal conditions. It can be carried out from 10 weeks of pregnancy, uses only a simple blood sample, and poses no risk to mother or baby.

Using a simple maternal blood sample, this advanced test analyses your baby’s DNA to assess the risk of:

  • Down Syndrome (Trisomy 21)
  • Edwards Syndrome (Trisomy 18)
  • Patau Syndrome (Trisomy 13)

Get peace of mind early in your pregnancy with fast, reliable results.

What Is a Non-Invasive Prenatal Test (NIPT)?

Non-Invasive Prenatal Testing (NIPT) is an advanced screening test that analyses cell-free foetal DNA found in the mother’s bloodstream.

This technology uses Next Generation Sequencing (NGS) and sophisticated bioinformatics to detect chromosomal abnormalities with exceptional accuracy – without any invasive procedures.

Unlike procedures such as amniocentesis, NIPT carries no risk of miscarriage and can be performed early in pregnancy.

What Conditions Does NIPT Screen For?

NIPT Basic £279

Screens for the three most common chromosomal conditions:

  • Trisomy 21 (Down Syndrome): A condition associated with developmental delay and characteristic physical features caused by an extra copy of chromosome 21.
  • Trisomy 18 (Edwards Syndrome): A serious condition often linked to severe medical complications caused by an extra copy of chromosome 18.
  • Trisomy 13 (Patau Syndrome): A rare but severe condition affecting multiple organs caused by an extra copy of chromosome 13.

NIPT Plus £349

Includes everything in NIPT Basic, plus:

Sex Chromosome Aneuploidies

  • Turner Syndrome (X0)
  • Klinefelter Syndrome (XXY)
  • Triple X Syndrome (XXX)
  • XYY Syndrome

Microdeletion Syndromes

Including:

  • 1p36 Deletion Syndrome
  • DiGeorge Syndrome
  • Wolf–Hirschhorn Syndrome
  • Cri du Chat Syndrome
  • Angelman Syndrome
  • Prader–Willi Syndrome

Additional Microdeletion & Microduplication Syndromes

87 additional conditions screened for enhanced reassurance. Examples include:

  • Smith–Magenis Syndrome
  • 3 Microduplication Syndrome
  • 1p32–p31 Deletion Syndrome
  • Alagille Syndrome
  • Langer–Giedion Syndrome

Understanding Chromosomal Conditions

Chromosomal abnormalities occur when there is an extra or missing chromosome.

  • Down Syndrome (T21) – babies can survive to birth but may have developmental challenges
  • Edwards Syndrome (T18) and Patau Syndrome (T13) – often associated with severe complications

The likelihood of these conditions increases with maternal age.

Who is the Prenatal Screening Test For?

NIPT is suitable for:

  • Pregnant women aged 35 or over
  • Those with high-risk screening results
  • IVF pregnancies
  • Women with a history of miscarriage
  • Those with a family or pregnancy history involving chromosomal abnormalities
  • Anyone seeking early reassurance without invasive testing

Why Choose the AffinityDNA NIPT?

Pregnancy can be an emotional time, especially when you are waiting for answers. Our NIPT is designed to provide early reassurance, with a professional, confidential service and easy-to-understand results. Please speak to our team who will assist you with any questions you may have.

✔ Highly Accurate

Detection rate of ≥99.9% for major trisomies using advanced sequencing technology.

✔ Completely Safe

No risk to your baby and no invasive procedure required – just a simple blood test.

✔ Early Testing

Available from 10 weeks of pregnancy.

✔ Fast Results

Receive your results within 5-7 working days from receipt of samples at the laboratory.

✔ Flexible Options

Choose between Basic or Plus depending on the level of detail you want.

✔ Optional Baby Gender Report

Choose to discover your baby’s gender at no additional cost.

What’s Included in the NIPT Kit?

The prenatal kit contains everything you need to collect your DNA samples and return them to us:

    1. 2 blood tubes for the mother’s blood samples
    2. Instructions
    3. Consent forms
    4. Prepaid return courier pouch

The mother’s samples must be collected via a medical blood draw which will need to be carried out by a doctor or a nurse. It is a standard blood draw from the arm, and we can arrange for a nurse to visit you at home if you prefer not to use your own GP. There is an additional charge for this service which varies depending on location. Please Contact Us for more information and a quotation.

Once you have all samples ready, they can be returned to our laboratory using the pre-paid courier pouch included with your kit.

How Does NIPT Work?

    1. Order your test: Choose your package and arrange your appointment.
    1. Arrange sample collection: A trained professional collects a small blood sample (2x 10ml).
    1. Laboratory analysis: Foetal DNA is extracted and analysed using advanced sequencing.
    1. Bioinformatics processing: Data is assessed to detect chromosomal abnormalities.
    1. Receive your results: Clear, confidential report delivered within 5–7 working days.

NIPT Clinical Guidance & Next Steps

While the Non-Invasive Prenatal Test (NIPT) is a highly accurate screening test, it is not a diagnostic test. If your results indicate a high risk for a chromosomal condition, it is important to seek further medical advice.

We strongly recommend that you consult your GP, midwife, or healthcare professional, who can guide you on appropriate next steps, including any confirmatory diagnostic testing if required.

Optional NIPT Premium Package

For complete peace of mind, combine:

  • NIPT Plus (chromosomal screening)
  • Non-Invasive Prenatal Paternity Test
  • Baby Gender Test (optional)

All for £899 from a single blood sample, with no risk.

IMPORTANT: The Premium Package is only available from 10 weeks of pregnancy.

Frequently Asked Questions

Is NIPT a diagnostic test?

No.  The NIPT is a high accuracy screening test, not a diagnostic procedure. It estimates the likelihood of chromosomal abnormalities by analysing cell free foetal DNA in maternal blood. High-risk results should be confirmed with further testing.

When can I take the NIPT test?

From 10 weeks of pregnancy. This timing ensures there is enough foetal DNA circulating in the mother’s bloodstream for accurate analysis.

Is NIPT safe for me and my baby?

Yes – NIPT is completely non-invasive and only requires a blood sample from the mother. It poses no risk of miscarriage.

How long do NIPT results take?

Results are typically delivered within 5-7 working days after the laboratory receives your sample. This fast turnaround allows expectant parents to gain early reassurance.

How accurate is NIPT?

The test offers ≥99.9% detection rate for major trisomies, thanks to advanced Next Generation Sequencing (NGS) and digitalised quality control.

What sample is needed?

A maternal blood sample is required.

Can I find out my baby’s gender?

Yes. Gender determination is available at no additional cost. This is based on the detection of Y chromosome material in the maternal blood sample.

Does maternal age affect the risk of chromosomal abnormalities?

Yes. The risk of chromosomal aneuploidy increases with maternal age due to nondisjunction events.

Can NIPT detect all genetic conditions?

No. While the NIPT is highly comprehensive, it cannot detect all genetic disorders. It focuses on chromosomal abnormalities detectable through cell free DNA analysis. Conditions caused by single gene mutations (e.g., cystic fibrosis) are not included unless part of a separate test.

What factors can affect the accuracy of the test?

Several factors may influence the foetal fraction and therefore the accuracy of the test, including:

  • Early gestational age
  • High maternal BMI
  • Certain medications
  • IVF pregnancies

Can I do the NIPT test if I am expecting twins?

Yes, but blood samples must be collected from 12 weeks of pregnancy.

What is the difference between NIPT Basic and NIPT Plus?

NIPT Basic screens for the three major trisomies.
NIPT Plus includes Basic + 4 sex chromosome aneuploidies + 93 microdeletion & microduplication syndromes.

What should I do if I receive a high-risk NIPT result?

If your NIPT result indicates a high risk for a chromosomal condition, we recommend that you contact your GP, midwife, or healthcare provider as soon as possible. They will be able to discuss your results in detail and may recommend further diagnostic testing, such as amniocentesis or CVS, to confirm the result. It is important to remember that NIPT is a screening test and not a definitive diagnosis.

Book Your NIPT Test Today

Take control of your pregnancy journey with a test that is:

  • Safe
  • Accurate
  • Fast
  • Trusted

Order your NIPT today from £279 and get the reassurance you deserve.

Other Non-Invasive Prenatal Tests from AffinityDNA

Prenatal Paternity Test

Our Non-Invasive Prenatal Paternity Test is a cutting-edge test that makes it possible for you to confirm if the man you suspect to be the father of your baby is the biological father. Available from the 7th week of pregnancy, you can get the answer you need with a risk-free DNA test.

Please click here to read more about our Prenatal Paternity Test.

Baby Gender Test

Our new and improved non-invasive Early Baby Gender Test is highly sensitive and is now 99.5% accurate.

You can take the test as early as the 7th week of pregnancy (49-56 days from the first day of the mother’s last menstrual cycle).

Results take only 7 working days, and an express service is available to receive results in just 4 working days.

Please click here to read more about our Baby Gender DNA Test.

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